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Primary Care Predicaments: Myopathies, Neuropathies & Neuromuscular Conditions, Oh My!
From ALS to myasthenia gravis to Guillain-Barré syndrome, potentially aggressive neuromuscular disorders can present with a range of nebulous symptoms.
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New Discovery Reveals Pathway to Modulate Scarring in Spinal Cord Injury
After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it
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Forecasting May Help People with Epilepsy Predict Their Seizures
UCSF team discovers brain activity patterns that foreshadow seizures up to 24 hours before they occur.
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ER Visit Leads to Moyamoya Disease Diagnosis and Personalized Treatment Plan: UCSF Case Study
A 47-year-old woman came to the UCSF emergency department with acute slurred speech along with left-sided facial droop and left-sided numbness, suggesting a stroke. Vessel imaging showed bilateral obstructive arteriopathy, an indication of moyamoya disease.
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Life-Changing Care for Untreated Spinal Muscular Atrophy: UCSF Case Study
An adult man with spinal muscular atrophy (SMA) had been born with limb weakness that progressed to respiratory muscle weakness. Though able to sit independently since childhood, he was never able to walk. Due to the high cost of medication in his home country, he was unable to receive treatment, so he moved to the United States at age 36 to seek therapy for his SMA.
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Inpatient Infusion Therapy for Refractory Headaches: UCSF Case Study
The first center of its kind on the West Coast, the UCSF Headache Center provides patients with comprehensive care to relieve the most debilitating headaches. This includes inpatient treatment for people with severe unremitting or recurring headaches for whom first-line therapies have failed.
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Improving Measurement of Parkinson’s Disease Severity with AI
Despite recent advancements in the treatment of Parkinson’s Disease, it remains a challenge to accurately measure the progression of symptoms in this neurological disorder.
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Interdisciplinary Vasculopathy Care
The UCSF Vasculopathy Clinic provides comprehensive, interdisciplinary care for patients with moyamoya disease, atherosclerosis and other conditions that cause intracranial vasculopathy.
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Signs of Multiple Sclerosis Show Up in Blood Years Before Symptoms
In a discovery that could hasten treatment for patients with multiple sclerosis (MS), UC San Francisco scientists have discovered a harbinger in the blood of some people who later went on to develop the disease.
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New Predictive MS Blood Test May Help Prevent Disability Worsening
Patients with multiple sclerosis (MS) whose blood tests reveal elevated neurofilament light chain (NfL), a biomarker of nerve damage, are at risk of experiencing disability worsening one to two years later, according to a new study spearheaded by UCSF researchers.
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New Alzheimer’s Trial to Combine Anti-Amyloid and Anti-Tau Therapies to Arrest Disease Progression
A new study will combine an Alzheimer’s medication that slows disease progression in some patients with two drugs that target disease-driving proteins to see whether their effects can be amplified.
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Why Has Progress in the Treatment of Alzheimer’s Disease Taken 30 Years?
UCSF expert examines the past and future of clinical trials for Alzheimer’s Disease.
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Telehealth Referral Leads to Diagnosis and Effective Treatment of Rare Neuropathy: Case Study
A 68-year-old man from Hawaii with acetylcholine receptor (AChR) antibody–positive myasthenia gravis and poorly controlled type 2 diabetes complicated by neuropathy had been receiving intravenous immunoglobulin (IVIg) and taking pyridostigmine for two years when ...
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Center for Encephalitis and Meningitis
The UCSF Center for Encephalitis and Meningitis provides comprehensive services to diagnose and treat patients with challenging neuroinflammatory disorders.
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UCSF Neurologist Recognized for Innovative Epilepsy Research
UCSF Neurologist Recognized for Innovative Epilepsy Research American Academy of Neurology to Honor Jon Kleen, MD, PhD with 2023 Dreifuss-Penry Epilepsy Award
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Electroconvulsive Therapy for Status Epilepticus and a Genetic Diagnosis for Epilepsy and Renal Failure: UCSF Neurohospitalist Cases
One of the first of its kind, the UCSF Neurohospitalist Program specializes in caring for hospitalized patients with complex neurologic disorders.
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Minimally Invasive LITT Effective for Recurrent Glioblastoma: A UCSF Case Study
A 65-year-old woman with a small focal recurrence of glioblastoma was treated with laser interstitial thermal therapy (LITT) at UCSF nearly five years after her first tumor resection surgery.
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Drug Targeting Tauopathies in Mice Reveals Sex Differences in Response
Microglia are cells that are central to both brain health as well as disease progression in many neurological conditions.
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Aggressive Surgery Increases Survival with Low-Grade Brain Tumors
UCSF-Led study shows extensive resection results in longer survival for glioma patients
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Cerebral Cavernous Malformation Treatments Relieve Disparate Symptoms
Two patients with severe yet different neurological symptoms were referred to UCSF for emergent neurosurgical evaluation. Both were found to have previously undiagnosed cerebral cavernous malformations (CCMs), but each patient’s treatment was unique.
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First “Neuroprosthesis” Expands Vocabulary and Mobility for Man With Paralysis in New Milestone
The first “neuroprosthesis,” developed by UCSF researchers in 2021, translates brain signals from a man with severe paralysis directly into words that appear as text on a screen. Using this brain-machine interface, he can also move a robotic arm to manipulate objects.
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Assessing Cognitive Decline in Primary Care: New Tools and Algorithms for Everyday Practice
Although timely diagnosis can significantly improve a patient’s future, dementia is underdiagnosed and often detected late.
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Genomic Sequencing Is Changing Diagnosis, Treatment for Patients with Brain Cancer
Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy.
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DBS Restores Function for Parkinson’s Patient Through New “Sensing” Pacemaker: A UCSF Case Study
This study allows researchers to continuously record brain physiology from the DBS electrode and automatically adjust the stimulation intensity based on these signals.
