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Overview of Metagenomic Next-Generation Sequencing
Charles Chiu, MD, PhD, provides an overview of metagenomics next-generation sequencing (mNGS), a clinical test he and his UCSF colleagues have developed that allows millions of DNA sequences to be decoded from a single clinical sample.
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Clinical UCSF mNGS Assay for Diagnosis of Neurological Infections
Despite extensive conventional testing, acute neurological illness in hospitalized patients is difficult to diagnose. Charles Chiu, MD, PhD, discusses an mNGS test that identifies pathogens causing neurological infections from cerebrospinal ...
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Clinical Case Reports and New mNGS-Based Technologies
Charles Chiu, MD, PhD, discusses cases where mNGS testing saved the life of a patient with undiagnosed neuroleptospirosis, and spared another patient from a potentially unnecessary liver transplant.
