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New Research on Cell Regeneration Shows Promise for Treating Lung Injury and Fibrosis
In a new study, UCSF researchers showed that they could successfully redirect profibrotic murine lung cells to a nonfibrotic state in which they regenerated alveoli. These findings could lead to novel treatments for lung injury and fibrosis.
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UCSF Lung Transplant Patient No. 1,000 Looks Ahead to More of the Good Life
Hospital Innovations Boost 3-Year Survival From 50% in 2001 to 90% 20 Years Later
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Lung Cancer Screening: Who, How and When to Refer
†horacic radiologist Brett M. Elicker, MD, and thoracic surgeon Johannes Kratz, MD, present about current lung cancer screening guidelines: who, how, and when to refer.
News
Sorting Cancers by “Immune Archetypes” Represents Potential New Approach to Developing Precision Immunotherapies
Using data from over 300 patient tumors, UCSF researchers have described 12 classes of “immune archetypes” to classify cancer tumors. Their findings, published today in CELL, reveal that cancers from different parts of the body are immunologically similar to one another. These classifications provide unique strategies for enhancing each patient’s choice of cancer immunotherapies.
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UCSF-led Study Uncovers Unique Stem Cell Trajectory in Lungs Damaged by COVID-19 and Pulmonary Fibrosis
In a collaborative study between UCSF researchers appearing December 30 in Nature Cell Biology, UCSF researchers Jaymin Kathiriya, PhD, and Chaoqun Wang, PhD, discovered that severe lung injuries can trigger lung stem cells to undergo abnormal differentiation. Drs. Kathiriya and Wang, supervised by Hal Chapman, MD, and Tien Peng, MD, respectively, utilized stem cell organoid models to uncover a novel stem cell pathway that is seen in severely injured lungs from COVID-19 and idiopathic pulmonary fibrosis patients.
News
Activating Immune Surveillance Mechanisms Shows Promise for Treating Diabetes and Pulmonary Fibrosis
Researchers at UC San Francisco recently found that activating invariant natural killer T (iNKT) cells eliminated inflammatory senescent cells associated with chronic diseases in vivo. In the study, obese mice showed improved glucose control and mice with pulmonary fibrosis had decreased lung fibrosis and increased survival.
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Lung Transplant Outcomes at UCSF Among the Nation’s Best
For nine consecutive years, the UCSan FranciscoLung Transplant Program has achieved significantly higher-than-expected survival rates following transplant surgery. It is the only lung transplant program in the country with this record.
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Breathing Easier: An Update on Diagnosis and Management of Asthma
Allergist and immunologist Monica Tang, MD, discusses keys to distinguishing asthma from other disorders.
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Cardiac Surgery Program
The UCSF Cardiac Surgery Program is committed to surgical excellence, world-class patient care, pioneering research and education.
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Screening Guidelines for Common Cancers: A Lifesaving Update
In just 35 minutes, hematologist-oncologist Akshiv Malhotra, MD, presents the current recommendations on cervical, breast, colon and lung cancers, breaking down the test options for each and when to start tests based on a patient’s risk.
News
Virtual Monitoring for Lung Transplant Patients Aided by Home Spirometry Device
A new home spirometry kit combines a spirometer with a patient engagement platform to collect lung function data and symptoms remotely. This enables UCSF’s Lung Transplant team to remotely track patients with the goal of identifying both symptomatic and asymptomatic changes in lung function that may be the first sign of early chronic rejection.
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All About Allergies: Successful Diagnosis and Treatment
This breakdown of common allergies provides clarity on which patients to test and which tests to choose; how to effectively manage chronic allergies, such as allergic rhinitis; as well as signs and solutions for the many types of adverse food reactions.
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Lung Transplant Program
For nine consecutive years, the UCSF Lung Transplant Program has had significantly higher-than-expected post-surgery survival rates — the only program in the country with this record.
Document
Interstitial Lung Disease Program
Interstitial lung disease (ILD) patients at UCSF benefit from an internationally recognized team of ILD experts with the highest level of expertise in this rare and difficult-to-diagnose disease.
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Personalized Therapy for Early-Stage Lung Cancer at UCSF
Follow the journey of a UCSF patient with early-stage, high-risk lung cancer, from history to treatment and prognosis, including how surgeons chose to do a robotic assisted VATS lobectomy and an analysis of how well chemo is likely to work for her.
