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New ATS Recommendation: Use Race-Neutral Equations for Pulmonary Function Test Interpretation to Improve Patient Care
An American Thoracic Society (ATS) workshop committee, which included many UCSF researchers, recently released an official statement recommending the use of race-neutral average reference equations for pulmonary function test (PFT) interpretation.
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Drug Turns Cancer Gene Into "Eat Me" Flag for Immune System
UCSF-led study shows promising pre-clinical results in killing cancer cells resistant to current KRAS-targeted treatments.
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Personalizing Prostate Cancer Screening May Improve the Accuracy of Detection
The accuracy of prostate-specific antigen (PSA) screening for prostate cancer can be improved by accounting for genetic factors that cause changes in PSA levels that are not associated with cancer.
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Can What Works to Treat Cancer Work for Diabetes?
To live with type 1 diabetes is to be ruled by relentless routine. Food must be carefully monitored, and the only treatment, subcutaneous insulin, is burdensome...
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UCSF Health to Mark Thirty-Five Years of Heart Transplantation in 2024
In 2024, UC Health will celebrate 35 years of performing heart transplants. Since completing their first heart transplant in March 1989, UCSF surgeons have performed nearly 600, and along the way, the health system has become a recognized leader in treating heart failure and the sixth largest program for transplants in the nation.
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Rethinking How Cancer Cells Evade Targeted Therapy
Glioblastomas (GBMs) are incurable brain tumors with a prognosis of about one-and-a half years on average. They are highly resistant to treatment and have defied all attempts at precision therapy.
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UCSF Researchers Uncover New Pathway for Molecular Cancer Drug Therapies
In a study published December 8, 2022 in Science, UCSF researchers Kevin Lou, an MD-PhD student, Luke Gilbert, PhD, and Kevan Shokat, PhD, reveal the discovery of a cellular uptake pathway important for larger molecules.
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Minimally Invasive LITT Effective for Recurrent Glioblastoma: A UCSF Case Study
A 65-year-old woman with a small focal recurrence of glioblastoma was treated with laser interstitial thermal therapy (LITT) at UCSF nearly five years after her first tumor resection surgery.
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“CAR Pooling” Screens Identify Most Effective Cancer Immunotherapy Cells
New approach by UCSF researchers analyzes how well different re-engineered T cells work against cancer.
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UCSF Case Study: Same-Day Discharge After Pheochromocytoma Removal
San Francisco endocrine surgeon Sanziana Roman, MD, performed a posterior retroperitoneoscopic adrenalectomy (PRA) to remove a pheochromocytoma. This approach enabled the patient to be discharged home within hours of surgery and avoid prolonged hospitalization, thereby minimizing COVID-19 risk.
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Hemodialysis Significantly Decreased for Patient with Primary Hyperoxaluria Type 1 in UCSF Study of Nedosiran
Researchers at UC San Francisco reported successful compassionate use of nedosiran to dramatically reduce plasma oxalate levels in a patient with primary hyperoxaluria type 1 (PH1).
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Novel Tricuspid and Mitral Valve Procedures Improve Patients' Quality of Life
UC San Francisco interventional cardiologists and interventional echocardiographers recently performed two novel minimally invasive cardiac procedures for the first time in the health system.
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UCSF500 Cancer Gene Panel Test
The UCSF500 Cancer Gene Panel leverages world-class expertise for advanced cancer cases. Designed by our leading cancer specialists, the UCSF500 offers unparalleled depth and precision in genetic analysis.
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Prenatal Enzyme Replacement Therapy for Lysosomal Storage Diseases
Pregnant patients with a diagnosed fetal lysosomal storage disease may have the opportunity to receive a promising treatment that could improve their babies’ health after birth.
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New Alzheimer’s Trial to Combine Anti-Amyloid and Anti-Tau Therapies to Arrest Disease Progression
A new study will combine an Alzheimer’s medication that slows disease progression in some patients with two drugs that target disease-driving proteins to see whether their effects can be amplified.
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How a Cardiogenic Shock Rapid Transfer Protocol Enables Lifesaving Patient Care: Case Study
UCSF has a rapid transfer protocol in place, which includes immediate access to a critical care cardiologist, expedited triage and a dedicated unit for patients transferring in for emergent care.
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Can AI Predict Serious Adverse Events From IBD Therapies?
In a groundbreaking study, UCSF researchers used a new clinical large language model (LLM) to identify serious adverse events (SAEs) occurring in patients treated with immunosuppressants to manage inflammatory bowel disease (IBD).
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Novel Tricuspid Valve Procedure Improve Patients' Quality of Life and Health Status
UC San Francisco interventional cardiologists and interventional echocardiographers recently performed the health system’s first commercial transcatheter tricuspid valve replacement procedure using the Edwards Evoque system.
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UCSF’s Division of Cardiology to Partner with Rosenman Institute
UC San Francisco’s Division of Cardiology has joined with the Rosenman Institute to speed the development of health-tech innovation at UCSF.
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Activating Immune Surveillance Mechanisms Shows Promise for Treating Diabetes and Pulmonary Fibrosis
Researchers at UC San Francisco recently found that activating invariant natural killer T (iNKT) cells eliminated inflammatory senescent cells associated with chronic diseases in vivo. In the study, obese mice showed improved glucose control and mice with pulmonary fibrosis had decreased lung fibrosis and increased survival.
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Screening and Removal of Precancerous Lesions Prevents Anal Cancer
National study led by UCSF is first to show effectiveness of simple strategies to reduce risk of often silent cancer.
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New Method for Rapid, Intraoperative Detection of Residual Tumor Cells Can Vastly Improve Patient Outcomes
It is now possible to detect residual tumor cells during surgery within minutes, a groundbreaking advancement in the surgical treatment of tumors.
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Neurovascular Disease and Stroke Center
Providing initial evaluations, second opinions and follow-up care for the prevention, diagnosis and treatment of stroke and other neurovascular conditions.
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Autoantibody for Acquired Lipodystrophy Identified, Bringing Hope for Therapeutics
UCSF investigators have found an autoantibody biomarker for acquired lipodystrophy, paving the way for novel treatment options for this complex condition, which causes adipose tissue loss and metabolic complications.
